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Staff Scientist, Analytical Chemistry at Regeneron Pharmaceuticals, Inc.
Dr. Xiaobin Xu is a Scientist at Regeneron Pharmaceuticals, Inc. He received his Ph. D. in degree in Analytical Chemistry from at Boston University, where he focused on proteomics and biological applications of mass spectrometry. At Regeneron, he leads and performs analytical characterization of therapeutic proteins to support pre-clinical and clinical development. He also develops new analytical methods and technologies to better characterize monoclonal antibodies (mAbs). His research interests include mass spectrometry based therapeutic protein/biomarker quantitation, hydrogen deuterium exchange mass spectrometry (HDX-MS) and chemical cross-linking mass spectrometry for protein conformation and protein-protein interaction studies, post-translational modifications, top-down mass spectrometry, host cell protein identification and quantification, separation of mAbs and mAb fragments, and bioanalytical method development and validation.