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Paul Peng is currently a principal scientist in Process Sciences Department at Alnylam Pharmaceuticals Inc. He obtained his Ph.D. in organic chemistry at McGill University, Montreal, Canada. His Ph.D. projects focused on chemical modifications of nucleosides, nucleotides and oligonucleotides for their therapeutic applications. He has been working on various projects in Drug Discovery, CMC and Process Sciences at Alnylam including siRNA lead optimization, synthesis and purification of large variety of novel chemically modified oligonucleotides and conjugates, process development for drug substance and drug product manufacturing.