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Brooke M. Rock is a Principal Scientist in the Department of Pharmacokinetics and Drug Metabolism at Amgen in South San Francisco. Brooke’s areas of scientific interest include: understanding of the mechanisms of cytochrome P450 oxidation reactions; the application of novel in vitro metabolism techniques to understand the enzymatic basis for biotransformation of potential therapeutic agents at the drug discovery interface; and the prospective application of in vitro data to predict clinically relevant pharmacokinetically based interactions. Brooke holds a BSc. and MS. in Biomedical Sciences from University of Michigan and Ph.D. in Medicinal Chemistry from the University of Washington. Brooke has co-authored more than 40 peer reviewed manuscripts and 4 book chapters.