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François defended his PhD in 1991, at the Pasteur Institute in Paris, in the lab of François Jacob. Then, he did his Post-doc at Genentech in the US. After that, he joined the GSK Research Institute of Geneva where he worked as a scientist in CNS research until 2001. His main field of interest was to validate metabotropic Glutamate receptors for CNS diseases. Then, he left GSK to found Addex Pharmaceuticals in Geneva, where he stayed CEO until 2005. Addex is a Biotech company dedicated to the discovery of novel treatments for CNS diseases and particularly focused on the development of mGluR5 antagonists. In 2005, he worked as an acting CEO for a VC firm in three different French Biotechs, before joining Merck Serono in September 2006 as Director, Early Stage Licensing, where he managed the in-licensing of several novel preclinical programs. François is the author of more than 40 peer reviewed scientific articles and inventor in 2 patents.