Karen BucklandLead Scientist, Gene & Cell Therapy at NIHR Great Ormond Street Hospital Biomedical Research Centre, UK
Karen Buckland obtained a BSc Physiology & Pharmacology 2000 awarded by University college London. 2004 she was awarded PhD Pharmacology by Imperial College London, which was funded by and research carried out in collaboration with UCB. Thesis focussed on leukocyte function, histamine receptors and PGD2. 2004-2006 Postdoctoral research in models of Allergy & Asthma at the University of Michigan. 2006-2008 further research at Imperial College London in collaboration with various industrial partners. 2008-2009 employed as senior researcher at Institute of Child Health, UCL. 2009 to present lead scientist at the Great Ormond Street Hospital Biomedical Research Centre a joint venture between UCL and GOSH. Conducting autologous ATMP manufacture for clinical trials in primary immune deficiencies and metabolic disorders. Hands on manufacture of 50+ ATMP batches, working with a range of academic and industry clinical trial sponsors, from set-up to manufacture to tech-transfer for ATMP projects. In her role as deputy Production Manager she has been responsible for internal project guidance for a range of ATMP products including skin, CAR-T and MSCs. Lastly, first-hand witness in the ‘spin out’ of a biotech that is now NASDAQ listed and retains an interest in the BRC facility.