Jonathan Royce - Business Leader - Chromatography Resins, GE HealthCare Life Sciences
Please note: The exhibit hall is not open following this talk. The exhibit hall opens today at 10:20am
Historically, the alkali stability of Protein A chromatography resins has lagged behind other resins used in downstream purification of antibody therapeutics. This fact, combined with the high nutrient load to which Protein A resins are exposed, introduces a larger risk of column contamination when compared with secondary and tertiary chromatographic operations. In this presentation, we present a newly designed protein A resin which offers alkali stability on par with ion exchange and hydrophobic interaction chromatography resins. Data on binding capacity, caustic stability and resin cleanability will be presented.