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Jim Warwicker studied physics as an undergraduate, followed by a PhD in biochemistry, both of these at Bristol, UK. He became interested in computational biology and established models for calculating charge interactions in proteins. These ultimately formed the basis for the studies of protein solubility discussed in his talk at this conference. He has applied modelling methods to many structure-based problems in biochemistry, through post-doc work at Yale, and subsequent positions in Reading and Manchester in the UK. A theme of his computational work is to be informed by experiment, which is certainly true when developing software to help the bioprocessing industry.