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Jonathan Bones, Ph.D.

Principal Investigator, NIBRT Characterization and Comparability Laboratory at National Institute for Bioprocessing Research & Training (NIBRT)

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Dr. Bones obtained his BSc in Analytical Science (Chemistry) and PhD in Analytical Chemistry from Dublin City University (DCU) under the guidance of Prof. Brett Paull. Following completion of his doctoral studies, Jonathan took a position at the Center for Bioanalytical Science in DCU, focused on the development and application of long monolithic silica columns for high efficiency LC-MS profiling of cell culture media, a collaboration with Bristol Myers Squibb.

Jonathan joined Prof. Pauline M. Rudds group at NIBRT in 2007 based at the UCD Conway Institute of Biomolecular and Biomedical Research, representing NIBRT in the EU FP6 GLYFDIS – ‘Glycans in Bodily Fluids, Potential for Disease Diagnostics’ Consortium before becoming the GlycoAnalytical Team Leader within the Dublin-Oxford Glycobiology Laboratory.

In 2010 Jonathan was appointed as the ‘John Hatsopoulos Research Scholarship’ at the Barnett Institute of Chemical and Biological Analysis at Northeastern University in Boston, MA, working under the mentorship of Prof. Barry L. Karger investigating new approaches for glycomics and the application of proteomics for a better understanding of mammalian cell bioprocessing.

Jonathan returned to NIBRT in 2012 following receipt of a ‘Starting Investigator Research Grant’ from Science Foundation Ireland and is currently exploring the use of ‘omics’ to identify molecular manifestations in Chinese Hamster Ovary (CHO) cells which potentially result in altered product yield and quality under altered bioprocess conditions.

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