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Friedrich Koch-Nolte is professor of Immunology and Molecular Biology at the University Medical Center Hamburg-Eppendorf, Hamburg (Germany). Work in his lab focuses on extracellular ATP and NAD+ as a danger signals in the immune system and on the ecto-enzymes and receptors that respond to these nucleotides. In addition, his group engineers nanobodies as anti-tumor therapeutics and as tools to modulate the function of enzymes and ion channels.